Effectiveness and Tolerance of Enteral Nutrition in Critically Ill COVID-19 Patients
Author Information
Author(s): Pérez-Cruz Elizabeth, Ortiz-Gutiérrez Salvador, Castañón-González Jorge Alberto, Luna-Camacho Yuritzy, Garduño-López Jessica
Primary Institution: Hospital Juárez de México, México City, Mexico
Hypothesis
An enteral feeding formula IMM in COVID-19 patients ventilated in ICU and prone position would be associated with achieving an optimal amount defined as 80% of the 24-h protein and calorie target.
Conclusion
The study found that enteral nutrition is a safe and well-tolerated intervention, with the ω3 formula improving protein and calorie targets compared to other formulas.
Supporting Evidence
- The ω3 group achieved the highest percentage of patients meeting caloric and protein targets.
- Mechanical ventilation-free time was significantly longer in the ω3 and MD groups compared to the IMM group.
- Diarrhoea and gastroparesis rates were lower in the ω3 group compared to the other groups.
Takeaway
This study shows that giving special nutrition to very sick COVID-19 patients helps them get the energy and protein they need to get better.
Methodology
A prospective cohort study was conducted on consecutive adult patients with severe SARS-CoV-2 infection admitted to the ICU, comparing three enteral formulas.
Potential Biases
The study may have selection bias due to being conducted in a single referral hospital.
Limitations
The study was conducted at a single hospital, which may introduce selection biases, and the results may not be generalizable to other settings.
Participant Demographics
The majority of participants were overweight or had obesity, with many having chronic diseases like hypertension and diabetes.
Statistical Information
P-Value
p<0.001
Confidence Interval
95% CI 22.1, 22.9
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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