Prediction of volume response under open-chest conditions during coronary artery bypass surgery
2007

Predicting Fluid Needs During Heart Surgery

Sample size: 40 publication 10 minutes Evidence: high

Author Information

Author(s): Sander Michael, Spies Claudia D, Berger Katharina, Grubitzsch Herko, Foer Achim, Krämer Michael, Carl Matthias, Heymann Christian

Primary Institution: Charité Universitätsmedizin Berlin

Hypothesis

Can CVP, PCWP, GEDVI, SVV, and PPV effectively predict changes in cardiac index and stroke volume index after sternotomy in cardiac surgery patients?

Conclusion

CVP and PCWP are not suitable for monitoring fluid status during cardiac surgery, while GEDVI, SVV, and PPV are more reliable indicators.

Supporting Evidence

  • CVP and PCWP did not correlate with changes in cardiac index after sternotomy.
  • GEDVI, SVV, and PPV showed significant correlations with changes in cardiac index.
  • Only relative changes in GEDVI, SVV, and PPV predicted an increase in stroke volume index.

Takeaway

Doctors need to use better tools than CVP and PCWP to check if heart surgery patients need more fluids, especially after opening the chest.

Methodology

Measured CVP, PCWP, GEDVI, SVV, and CI in 40 patients at two time points: after anesthesia induction and after sternotomy.

Limitations

The study did not measure catecholamine discharge or chest wall compliance changes post-sternotomy.

Participant Demographics

Mean age 63 years, 36 males and 4 females, average height 1.75 m, average weight 90 kg.

Statistical Information

P-Value

<0.01

Confidence Interval

95% confidence interval for GEDVI delta: 0.61–0.91

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/cc6181

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication