Nephrotic syndrome and kidney failure due to immunocomplex-mediated renal damage in a patient with Waldenström's Macroglobulinemia: a case report
2008

Kidney Damage in Waldenström's Macroglobulinemia: A Case Report

Sample size: 1 publication Evidence: low

Author Information

Author(s): Hector Castro, Rafael Valenzuela, Phillip Ruiz, Oliver Lenz, Mauricio Monrroy

Primary Institution: University of Miami/Jackson Memorial Medical Center

Hypothesis

Can Waldenström's Macroglobulinemia lead to nephrotic syndrome and kidney failure?

Conclusion

This case illustrates an unusual instance of kidney damage in a patient with Waldenström's Macroglobulinemia, resulting in nephrotic syndrome and chronic renal insufficiency.

Supporting Evidence

  • The patient presented with nephrotic syndrome and renal insufficiency.
  • Histopathological findings were similar to those seen in mesangiocapillary glomerulonephritis type III.
  • Nephrotic syndrome is a rare manifestation in patients with Waldenström's Macroglobulinemia.

Takeaway

A man with a rare blood cancer had serious kidney problems that are not usually seen with this disease.

Methodology

Case report detailing clinical presentation, laboratory findings, and histopathological examination.

Limitations

The findings are based on a single case, limiting generalizability.

Participant Demographics

60-year-old Hispanic male.

Digital Object Identifier (DOI)

10.1186/1757-1626-1-333

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