Comparing Two Contrast Agents for MR Angiography
Author Information
Author(s): Seeger Achim, Kramer Ulrich, Fenchel Michael, Grimm Florian, Bretschneider Christiane, Döring Jörg, Klumpp Bernhard, Tepe Gunnar, Rittig Kilian, Seidensticker Peter R, Claussen Claus D, Miller Stephan
Primary Institution: Eberhard-Karls-University Tuebingen
Hypothesis
Is there a difference in image quality and diagnostic accuracy between a macrocyclic and a linear contrast agent in whole body MR angiography?
Conclusion
Both contrast agents provided high diagnostic accuracy with no significant difference in image quality.
Supporting Evidence
- Both contrast agents yielded diagnostic image quality.
- Diagnostic accuracy was 95% for both contrast agents.
- Overall sensitivity/specificity for gadopentetate dimeglumine was 93%/95% and for gadobutrol was 94%/94%.
Takeaway
Doctors tested two types of contrast agents to see which one gives better pictures of blood vessels during MR scans, and they found both worked well.
Methodology
Retrospective analysis of 165 patients who underwent DSA and WBMRA using either gadopentetate dimeglumine or gadobutrol.
Limitations
The study relied on qualitative parameters rather than quantitative measurements like signal-to-noise ratio.
Participant Demographics
Mean age was 66 years for gadopentetate dimeglumine group and 67 years for gadobutrol group, with a mix of male and female patients.
Statistical Information
Statistical Significance
p = n.s.
Digital Object Identifier (DOI)
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