Microbial Pathogen Microarray Facility Progress
Author Information
Author(s): Philip Butcher, Joseph Mangan, Sarah Husain, Brendan Wren, Keith Vass, Ceridwen Davies, Neil Stoker, Jason Hinds
Primary Institution: St. George's Hospital Medical School
Conclusion
The microbial pathogen microarray group has made significant progress in developing microarrays for various bacterial pathogens.
Supporting Evidence
- Microarrays for Mycobacterium tuberculosis, Campylobacter jejuni, Haemophilus influenzae and Yersinia pestis are already in use.
- Most talks at the meeting described the use of these arrays in comparative genomics and gene expression profiling studies.
Takeaway
Scientists are working together to create special slides that help study germs, and they've already made good progress in the last year.
Methodology
The group is constructing whole genome glass slide microarrays for 12 bacterial pathogens and providing training to collaborators.
Limitations
Data analysis from microarrays has been identified as a bottleneck.
Participant Demographics
Over 30 collaborating groups from the UK are involved.
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