Cetuximab for Metastatic Mucoepidermoid Carcinoma
Author Information
Author(s): Salvatore Grisanti, Vito Amoroso, Michela Buglione, Anna Rosati, Roberto Gatta, Claudio Pizzocaro, Vittorio D Ferrari, Giovanni Marini
Primary Institution: Azienda Spedali Civili, Brescia, Italy
Hypothesis
Is cetuximab effective in treating metastatic mucoepidermoid carcinoma of the salivary glands?
Conclusion
Cetuximab can be active in mucoepidermoid carcinoma and may restore sensitivity to cisplatin in patients previously treated with platinum-based chemotherapy.
Supporting Evidence
- The patient had distant bone and visceral metastases despite previous chemotherapy.
- Cetuximab was administered in combination with cisplatin.
- A partial response was documented at all extracranial metastatic sites after treatment.
Takeaway
A man with a rare type of cancer got better after taking a medicine called cetuximab, even though he had already tried other treatments that didn't work.
Methodology
The patient was treated with cetuximab and cisplatin after failing previous chemotherapy.
Limitations
The study is based on a single case report, limiting generalizability.
Participant Demographics
40-year-old Caucasian man
Digital Object Identifier (DOI)
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