Understanding Metabolic Disorders in Osteoarthritis
Author Information
Author(s): Yu Congcong, Zhao Siyu, Yue Songkai, Chen Xiaoyang, Dong Yonghui
Primary Institution: Department of Orthopedics, Henan Provincial People’s Hospital, Zhengzhou University People’s Hospital, Zhengzhou, China
Hypothesis
Metabolic syndrome and its components significantly influence the pathogenesis and progression of osteoarthritis.
Conclusion
The review highlights the critical role of metabolic disorders in osteoarthritis and suggests that improving these disorders may benefit treatment outcomes.
Supporting Evidence
- More than 300 million people worldwide suffer from osteoarthritis.
- Metabolic syndrome components like obesity and hypertension are linked to the prevalence and progression of osteoarthritis.
- Understanding metabolic disorders can lead to better treatment strategies for osteoarthritis.
Takeaway
Osteoarthritis is a common joint problem that can be worsened by issues like obesity and diabetes, and understanding these connections can help find better treatments.
Methodology
A systematic review of literature related to metabolic syndrome and osteoarthritis was conducted using PubMed, focusing on studies published until October 2024.
Potential Biases
Potential bias due to the exclusion of non-English studies and the reliance on published literature.
Limitations
The review primarily includes studies in English and may not encompass all relevant research published in other languages.
Participant Demographics
The study included a diverse population with over 300 million individuals affected by osteoarthritis globally.
Digital Object Identifier (DOI)
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