Propofol-Induced Hyperglycemia in the Critically Ill: An Unfamiliar Side Effect of a Common Anesthetic
2024

Propofol-Induced Hyperglycemia in Critically Ill Patients

Sample size: 1 publication Evidence: low

Author Information

Author(s): Muacevic Alexander, Adler John R, Qureshi Muhammad A, Thomas Greeshma A, Mathew Tijin, Anshul FNU

Primary Institution: Southeast Health Medical Center, Dothan, USA

Hypothesis

Does propofol cause hyperglycemia in critically ill patients?

Conclusion

Propofol can induce hyperglycemia in critically ill patients, impacting their treatment and outcomes.

Supporting Evidence

  • Propofol is commonly used in the ICU and may lead to hyperglycemia.
  • Animal studies suggest propofol induces insulin resistance.
  • The patient's blood glucose spiked after starting propofol sedation.
  • Discontinuation of propofol led to improved blood glucose levels.

Takeaway

When doctors use a common sedative called propofol in very sick patients, it can make their blood sugar go too high, which is not good for them.

Methodology

Case report of a 58-year-old female patient with hyperglycemia after receiving propofol for sedation.

Potential Biases

Limited evidence from human studies may introduce bias in understanding the effects of propofol.

Limitations

The study is based on a single case and lacks extensive human trials.

Participant Demographics

One 58-year-old female patient with a history of diabetes and other health issues.

Digital Object Identifier (DOI)

10.7759/cureus.74263

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication