Comparative analysis of clinical characteristics of symptomatic pituitary adenomas in elderly patients: a consecutive series of 114 patients
2024

Clinical Characteristics of Pituitary Adenomas in Elderly Patients

Sample size: 114 publication Evidence: moderate

Author Information

Author(s): Wang Run, Han Xiaodi, Xie Cheng, Zhang Qinghua, Kan Liang, Han Sheng

Primary Institution: The First Hospital of China Medical University

Hypothesis

Elderly patients with pituitary adenomas have unique clinical characteristics that affect their diagnosis and treatment.

Conclusion

Elderly patients with pituitary adenomas often experience worse pre- and post-operative conditions, highlighting the need for early surgical intervention.

Supporting Evidence

  • 61.4% of patients experienced vision impairment preoperatively.
  • 73.7% of tumors were non-functional pituitary adenomas.
  • Elderly patients had a higher rate of postoperative complications compared to younger patients.

Takeaway

Older people with pituitary tumors often have vision problems and need surgery sooner to help them see better.

Methodology

This study analyzed clinical data from 114 elderly patients who underwent surgery for pituitary adenomas, comparing younger and elder groups based on age.

Limitations

The study is a single-center retrospective analysis, limiting the generalizability of the findings.

Participant Demographics

65 males (57.0%) and 49 females (43.0%), average age 73.2 years.

Statistical Information

P-Value

P=0.001

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3389/fendo.2024.1385813

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