Genome-Wide Expression Patterns and the Genetic Architecture of a Fundamental Social Trait
2008

Gene Expression Patterns for a Social Trait

Sample size: 40 publication 10 minutes Evidence: high

Author Information

Author(s): John Wang, Kenneth G. Ross, Laurent Keller

Primary Institution: University of Lausanne

Hypothesis

How do interactions between genes and the environment influence social behavior in fire ants?

Conclusion

The study found that worker gene expression profiles in fire ants are more strongly influenced by the social environment than by their own genotype.

Supporting Evidence

  • Differences in Gp-9 genotype are associated with the differential expression of a small number of genes.
  • Worker gene expression profiles are influenced more by the social environment than by their own Gp-9 genotype.
  • An unusual example of an 'extended phenotype' was observed.

Takeaway

Fire ants can have different social behaviors based on their genes, and how they behave is also affected by the other ants around them.

Methodology

Microarray analyses were performed on adult workers from polygyne and monogyne colonies to compare gene expression profiles.

Potential Biases

Potential bias due to the colony-level effects on gene expression.

Limitations

The use of whole worker bodies may decrease the probability of detecting genes with variable expression among cells or tissues.

Participant Demographics

Adult workers from 20 polygyne and 20 monogyne colonies.

Statistical Information

P-Value

1.17E-04

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1371/journal.pgen.1000127

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