Childhood Cancer and Air Pollution in Southeast Texas
Author Information
Author(s): Kristina W. Whitworth, Elaine Symanski, Ann L. Coker
Primary Institution: University of Texas School of Public Health
Hypothesis
Do census tracts with the highest benzene or 1,3-butadiene ambient air levels have increased childhood lymphohematopoietic cancer incidence?
Conclusion
The study suggests an association between childhood leukemia and hazardous air pollution.
Supporting Evidence
- Census tracts with the highest benzene levels had elevated rates of all leukemia.
- The association was stronger for acute myeloid leukemia than for acute lymphocytic leukemia.
- No associations were found between benzene or 1,3-butadiene levels and lymphoma incidence.
Takeaway
Kids living near high levels of certain air pollutants might get leukemia more often.
Methodology
The study used an ecologic analysis and Poisson regression models to assess cancer incidence in relation to air pollutant levels.
Potential Biases
Potential for bias due to the aggregate nature of the data and exposure misclassification.
Limitations
The study may be subject to ecologic fallacy and misclassification of socioeconomic status.
Participant Demographics
Children under 20 years of age diagnosed with lymphohematopoietic cancer in eight counties surrounding Houston, Texas.
Statistical Information
P-Value
0.03
Confidence Interval
95% CI, 1.05–1.78
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website