Efficacy of Endoscopic Cardia Peripheral Tissue Scar Formation in Treating GERD
Author Information
Author(s): Shi Chaoyi, Zhou Shunhai, Chen Xuanran, Shen Diyun, Wang Tianyue, ZhuoMa GeSang, Feng Mingzhi, Sun Yan, Zhang Jun
Primary Institution: The First Affiliated Hospital of Zhejiang Chinese Medical University
Hypothesis
This study aims to compare the efficacy of various endoscopic cardia peripheral tissue scar formation (ECSF) procedures in patients with gastroesophageal reflux disease (GERD).
Conclusion
PECC is the most effective ECSF procedure for improving GERD symptoms and has the lowest incidence of serious adverse events.
Supporting Evidence
- PECC significantly reduced GERD-Q scores compared to RF and ARMI.
- PECC increased lower esophageal pressure more than RF.
- All ECSF procedures had a low incidence of serious adverse events.
Takeaway
Doctors can use a special procedure called PECC to help people with a bad stomach problem called GERD feel better and have fewer side effects.
Methodology
This study conducted a systematic review and network meta-analysis of randomized controlled trials and cohort studies comparing ECSF procedures.
Potential Biases
Many studies did not provide details on blinding and allocation concealment, leading to potential bias.
Limitations
Some studies had small sample sizes and varying follow-up times, which may affect the reliability of the results.
Participant Demographics
The study included patients with GERD from various countries, primarily in Asia.
Statistical Information
P-Value
p<0.05
Confidence Interval
95% CI: [-3.02, -1.66]
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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