In Utero Exposure to Bioactive Food Components and Mammary Cancer Risk (R21)
2006
In Utero Exposure to Bioactive Food Components and Mammary Cancer Risk
publication
Evidence: moderate
Hypothesis
In utero exposures are important determinants of some cancers occurring in children and young adults.
Conclusion
Maternal diets and hormonal environments during pregnancy can significantly influence the risk of breast cancer in female offspring.
Supporting Evidence
- Maternal diets high in vegetables, fruits, and protein are linked to decreased risk of childhood leukemia.
- Birth weight is positively associated with breast cancer risk.
- Maternal preeclampsia has been associated with reduced risk of breast cancer in female offspring.
Takeaway
What a mom eats while pregnant can affect her baby's risk of getting breast cancer later in life.
Methodology
The study reviews epidemiological and preclinical evidence linking maternal nutrition and hormonal exposure during pregnancy to breast cancer risk in offspring.
Limitations
The effects of in utero exposure to dietary components have been inadequately examined.
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