SIGMA2: A system for the integrative genomic multi-dimensional analysis of cancer genomes, epigenomes, and transcriptomes
2008

SIGMA2: A Tool for Analyzing Cancer Genomes

publication Evidence: high

Author Information

Author(s): Chari Raj, Coe Bradley P, Wedseltoft Craig, Benetti Marie, Wilson Ian M, Vucic Emily A, MacAulay Calum, Ng Raymond T, Lam Wan L

Primary Institution: BC Cancer Agency Research Centre

Hypothesis

Can a software system be developed to integrate and analyze multi-dimensional cancer genomic data?

Conclusion

SIGMA2 enables the simultaneous identification of genetic alterations across multiple levels, enhancing the analysis of cancer biology.

Supporting Evidence

  • SIGMA2 allows for the integration of genomic, epigenomic, and transcriptomic data.
  • The software can analyze data from multiple platforms simultaneously.
  • It provides tools for visualizing complex data relationships in cancer research.

Takeaway

SIGMA2 is a computer program that helps scientists look at different types of cancer data all at once, making it easier to find important changes in genes.

Methodology

SIGMA2 integrates data from various 'omics disciplines, allowing for simultaneous visualization and analysis of multi-dimensional datasets.

Digital Object Identifier (DOI)

10.1186/1471-2105-9-422

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