Antibiotic Susceptibility Patterns of Streptomyces in Actinomycetoma
Author Information
Author(s): Hamid Mohamed E
Primary Institution: Department of Microbiology, College of Medicine, King Khalid University
Hypothesis
What are the antimicrobial susceptibility patterns among Streptomyces species causing actinomycetoma in humans and animals?
Conclusion
Streptomyces species causing actinomycetoma exhibit diverse susceptibility patterns to antimicrobial agents, complicating effective treatment selection.
Supporting Evidence
- All strains were inhibited by novobiocin, gentamycin, and doxycycline.
- 94.4% of the strains were inhibited by fusidic acid.
- All strains were resistant to amphotericin B, penicillin, and sulphamethoxazole.
Takeaway
This study looked at how different types of bacteria called Streptomyces respond to antibiotics in people and animals with a disease called actinomycetoma. It found that these bacteria can be very different in how they react to medicines.
Methodology
Streptomyces strains were tested in vitro against 15 commonly prescribed antibacterial agents using the MIC agar dilution method.
Limitations
The study may not cover all possible Streptomyces species and their susceptibility patterns.
Participant Demographics
Strains isolated from cases of actinomycetoma in humans and donkeys in Sudan.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website