The use of radiofrequency in cancer
2005

The Use of Radiofrequency in Cancer

Sample size: 215 publication Evidence: moderate

Author Information

Author(s): Gillams A R

Primary Institution: Department of Medical Imaging, The Middlesex Hospital, London, UK

Conclusion

Radiofrequency ablation (RFA) is an effective technique for minimally invasive destruction of tumors, particularly in patients who are not suitable for surgery.

Supporting Evidence

  • Radiofrequency ablation has been used effectively for treating hepatocellular carcinoma and colorectal liver metastases.
  • Complication rates for RFA are low, with a mortality rate of less than 0.8%.
  • Patients with limited but inoperable colorectal metastases have a 5-year survival rate of 26 to 30%.

Takeaway

Radiofrequency ablation is a way to destroy tumors using heat, and it can help patients who can't have surgery.

Methodology

The article reviews the effectiveness of radiofrequency ablation in various cancers, including liver, lung, and renal tumors, based on existing literature and patient outcomes.

Potential Biases

Potential bias in reporting outcomes from different centers and studies.

Limitations

The volume of tissue that can be ablated is limited, and the technique may not be suitable for all tumor types.

Participant Demographics

Patients with various types of cancer, including hepatocellular carcinoma, colorectal liver metastases, and renal cell carcinoma.

Statistical Information

P-Value

0.002

Statistical Significance

p=0.002

Digital Object Identifier (DOI)

10.1038/sj.bjc.6602582

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