Immunohistochemical testing for Helicobacter Pylori existence in neoplasms of the colon
2008

Helicobacter Pylori in Colon Polyps

Sample size: 51 publication Evidence: low

Author Information

Author(s): Soylu Aliye, Ozkara Selvinaz, Alıs Halil, Dolay Kemal, Kalaycı Mustafa, Yasar Nurgul, Kumbasar A Baki

Primary Institution: Bakirkoy Dr Sadi Konuk Training and Research Hospital, Istanbul, Turkey

Hypothesis

Is there a presence of Helicobacter pylori in neoplasms of the colon?

Conclusion

The presence of H. pylori in colon polyps did not yield any correlation with polyp size, colonic localization, or histopathologic type.

Supporting Evidence

  • 11 (21.6%) of the polyps were determined to be H. pylori positive.
  • The prevalence of H. pylori was higher in villous type polyps (60%) compared to other histologic types.
  • No significant correlation was determined between histologic types and prevalence of H. pylori.

Takeaway

This study looked for a germ called H. pylori in colon growths and found it in some, but it didn't seem to matter where the growths were or how big they were.

Methodology

The study used immunohistochemical methods to test biopsy specimens from patients who had colon polyps.

Limitations

The study had a small sample size and did not establish a significant correlation between H. pylori presence and polyp characteristics.

Participant Demographics

51 patients (19 male and 32 female) with a mean age of 61.88 years.

Statistical Information

Confidence Interval

95%

Statistical Significance

p > 0.05

Digital Object Identifier (DOI)

10.1186/1471-230X-8-35

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