Effects of Smoking and Hypertension on Fetal Growth
Author Information
Author(s): Rasmussen Svein, Irgens Lorentz M
Primary Institution: University of Bergen and the Norwegian Institute of Public Health
Hypothesis
How do smoking and hypertensive disorders affect fetal growth?
Conclusion
Smoking and hypertensive disorders generally do not work together to reduce fetal growth, suggesting they affect different mechanisms.
Supporting Evidence
- Smoking explained 12% of small for gestational age cases.
- Preeclampsia explained 21.9% of preterm cases of small for gestational age.
- The effect of early onset PIH was stronger than that of late onset.
Takeaway
Smoking and high blood pressure during pregnancy can make babies smaller, but they don't seem to make each other worse.
Methodology
Population-based study using records from the Medical Birth Registry of Norway.
Potential Biases
The study was based on registry data, which may not capture all relevant variables.
Limitations
Some risk factors for PIH and fetal growth restriction were not adjusted for in the analysis.
Participant Demographics
Included singleton pregnancies from the Medical Birth Registry of Norway.
Statistical Information
P-Value
p<0.05
Confidence Interval
95% confidence interval (0.9, 2.2)
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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