Effect of Diazepam Sedation on Oxygen Levels During Endoscopy
Author Information
Author(s): G. M. MALIK, M. MUBARIK, S. A. KADLA, J. A. BASU, H. TAJAMUL
Primary Institution: Government S.M.H.S. Hospital, Medical College, Srinagar, Kashmir, India
Hypothesis
Does intravenous diazepam sedation affect arterial oxygen saturation and patient tolerance during esophagogastroduodenoscopy?
Conclusion
Intravenous diazepam sedation may be a safe and favorable option for improving patient tolerance during esophagogastroduodenoscopy without significantly worsening oxygen saturation.
Supporting Evidence
- Diazepam sedation increased patient tolerance compared to controls.
- Arterial oxygen saturation showed a transient fall during the procedure.
- Sedation did not significantly worsen oxygen desaturation levels.
Takeaway
This study looked at how a medicine called diazepam helps people feel more comfortable during a tube procedure in their throat, without making their oxygen levels drop too much.
Methodology
The study involved 200 patients, with 100 receiving diazepam sedation and 100 acting as controls, measuring arterial oxygen saturation and procedure tolerance.
Limitations
The study was non-randomized and had strict exclusion criteria that may limit generalizability.
Participant Demographics
Patients aged 27-60 years, with equal numbers of males and females.
Statistical Information
P-Value
p<0.01
Statistical Significance
p<0.01
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