Anticoagulant and Anti-thrombotic Treatments in the Management of Hematological Malignancies in a Home Care Program
2011

Managing Blood Clots in Patients with Blood Cancers at Home

Sample size: 129 publication Evidence: moderate

Author Information

Author(s): Tendas Andrea, Cupelli Luca, Scaramucci Laura, Palombi Massimiliano, Trawinska Malgorzata, Monika Giovannini, Marco Brunetti, Gregorio Antonio, Cartoni Claudio, Bondanini Francesco, de Fabritiis Paolo, Niscola Pasquale

Primary Institution: Hematology Unit, S. Eugenio Hospital, Rome, Italy

Hypothesis

Can anticoagulant and anti-thrombotic treatments be safely administered to patients with hematological malignancies in a home care setting?

Conclusion

The use of anticoagulant and anti-platelet drugs in home care for patients with hematological malignancies rarely leads to significant complications.

Supporting Evidence

  • 20% of patients were treated with anticoagulant or anti-platelet drugs.
  • Adverse events were observed in 11.5% of treated patients.
  • None of the patients with bleeding complications had thrombocytopenia.

Takeaway

Doctors can give certain blood-thinning medicines to patients with blood cancers at home, and it usually doesn't cause serious problems.

Methodology

A prospective evaluation of anticoagulant and anti-thrombotic agents was conducted on patients followed at home during the first semester of 2010.

Limitations

The study was limited to a single-center and may not represent broader populations.

Participant Demographics

{"total_patients":129,"age_range":"20-98","gender_distribution":{"male":57,"female":72},"diagnoses":{"MDS/cMPD":53,"acute_leukemia":11,"lymphoma":18,"plasma_cell_dyscrasia":12,"cancer_unrelated_anemia":21,"other":14}}

Digital Object Identifier (DOI)

10.4103/0973-1075.78450

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