Dietary Nigella sativa nanoparticles enhance broiler growth performance, antioxidant capacity, immunity, gene expression modulation, and cecal microbiota during high ambient temperatures
2025

Effects of Nigella sativa Nanoparticles on Broiler Chickens

Sample size: 375 publication 10 minutes Evidence: high

Author Information

Author(s): Ahmed M. Elbaz, Eman S. Ashmawy, Farahat M. A. A., Abdel‑Maksoud Ahmed, Amin Shimaa A., Mohamed Zangabel S.

Primary Institution: Desert Research Center, Cairo, Egypt

Hypothesis

Adding Nano-Nigella sativa in broiler feed may play an important role as an effective alternative to antibiotics, in addition to reducing the impacts of heat stress on the chickens.

Conclusion

Supplementing broiler diets with Nigella sativa nanoparticles improves growth performance, immune responses, and gut health under high ambient temperatures.

Supporting Evidence

  • Nano-NS improved body weight gain and feed conversion ratio in broilers.
  • Serum HDL levels increased while total cholesterol and LDL decreased in broilers fed Nano-NS.
  • Nano-NS supplementation enhanced serum immunoglobulin levels and antioxidant enzyme activity.
  • Adding Nano-NS modulated gut microbiota, increasing Lactobacillus and decreasing E. coli.

Takeaway

Giving special tiny particles from black cumin to chickens helps them grow better and stay healthy when it's really hot outside.

Methodology

Broilers were divided into control and treatment groups, with varying levels of Nano-NS added to their diets, and their performance and health metrics were measured.

Potential Biases

Potential bias in the selection of treatment groups and environmental conditions.

Limitations

The study was conducted under controlled conditions, which may not fully represent real-world scenarios.

Participant Demographics

Male Ross 308 chicks, one-day-old.

Statistical Information

P-Value

<0.001

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1038/s41598-024-82725-9

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