Anti-inflammatory effects of Guava leaves
Author Information
Author(s): Sarmistha Dutta, Das Swarnamoni
Primary Institution: Assam Medical College and Hospital
Hypothesis
The study aims to evaluate the anti-inflammatory effect of the ethanolic extract of Psidium guajava leaves on experimental animal models.
Conclusion
The ethanolic extract of Psidium guajava leaves has significant anti-inflammatory activity.
Supporting Evidence
- The ethanolic extract of guava leaves showed significant inhibition of paw edema in acute inflammation.
- In subacute inflammation, guava leaves significantly reduced exudate formation.
- In chronic inflammation, guava leaves reduced both paw edema and weight loss in rats.
Takeaway
Guava leaves can help reduce swelling and inflammation in rats, which might be useful for treating similar issues in humans.
Methodology
The study involved four groups of rats treated with different doses of guava leaf extract and aspirin, and inflammation was induced using carrageenan and Freund's adjuvant.
Limitations
The study was conducted only on rats, and further research is needed to confirm the effects in humans.
Participant Demographics
Albino rats of the species Rattus norvegicus, weighing 150–200g.
Statistical Information
P-Value
<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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