Nutritional Prehabilitation in Bone Marrow Transplant Patients
Author Information
Author(s): Falcone Luca, Mancin Stefano, Azzolini Elena, Colotta Francesco, Ferrante Sergio, Pastore Manuela, Morales Palomares Sara, Lopane Diego, Sguanci Marco, Cosmai Simone, Cattani Daniela, Cereda Emanuele, Caccialanza Riccardo, Mazzoleni Beatrice
Primary Institution: Humanitas University
Hypothesis
Can nutritional prehabilitation improve clinical outcomes in hematological patients undergoing bone marrow transplantation?
Conclusion
Nutritional prehabilitation shows promise in improving outcomes for bone marrow transplant patients.
Supporting Evidence
- Nutritional interventions significantly increased energy intake and improved body weight.
- Clinical complications decreased, including severe acute graft-versus-host disease and pneumonia.
- The length of hospital stay was reduced with nutritional support.
- Overall survival improved with adherence to nutritional interventions.
Takeaway
This study found that helping patients eat better before and after their bone marrow transplant can make them feel better and recover faster.
Methodology
A systematic review of six studies evaluating nutritional interventions in bone marrow transplant patients.
Potential Biases
Low risk of bias in included studies, but variability in methodologies was present.
Limitations
Heterogeneity in treatment types and small sample sizes limited the evidence.
Participant Demographics
Patients with hematological diseases undergoing bone marrow transplantation.
Statistical Information
P-Value
p = 0.001
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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