Human Infection with Pseudoterranova azarasi Roundworm
Author Information
Author(s): Naoki Arizono, Toshiyuki Miura, Minoru Yamada, Tatsuya Tegoshi, Kotaro Onishi
Primary Institution: Kyoto Prefectural University of Medicine
Hypothesis
The study investigates the human infection caused by the Pseudoterranova azarasi roundworm and its identification.
Conclusion
The clinical isolate from a patient was confirmed to be Pseudoterranova azarasi, highlighting the risk of infection from consuming raw marine fish.
Supporting Evidence
- Pseudoterranova decipiens species complex is the second most common nematodes found in humans.
- The clinical isolate and larvae from Pacific cod were identified as P. azarasi.
- The geographic distribution of Pseudoterranova species varies, with P. azarasi found in the northwestern Pacific.
Takeaway
A woman in Japan got sick from a roundworm after eating raw fish, and scientists figured out it was a specific type of roundworm called Pseudoterranova azarasi.
Methodology
DNA was extracted from the clinical isolate and compared with isolates from Pacific cod using PCR and sequencing.
Limitations
The study is based on a single case report, limiting the generalizability of the findings.
Participant Demographics
The participant was a woman from Japan with no recent travel history.
Digital Object Identifier (DOI)
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