Structure of 5,6,7,8-Tetrahydroquinolin-8-one
Author Information
Author(s): Lipińska Teodozja M., Karczmarzyk Zbigniew, Wysocki Waldemar, Gruba Ewa, Fruziński Andrzej
Primary Institution: Department of Chemistry, University of Podlasie
Hypothesis
The study aims to report the X-ray structure of 5,6,7,8-tetrahydroquinolin-8-one.
Conclusion
The crystal structure of the compound shows no classical hydrogen bonds and features molecular layers with specific distances between them.
Supporting Evidence
- The compound is an important intermediate for the synthesis of polyheterocycles.
- It has pharmacological activity as a substrate for 8-amino substituted derivatives.
- The bond lengths and angles are within expected ranges.
- The aromatic pyridine ring is planar within 0.011 Å.
Takeaway
This study looks at a chemical compound and how its molecules are arranged in a solid form, showing that they stack in layers without certain types of bonds.
Methodology
X-ray diffraction analysis was used to determine the crystal structure.
Limitations
The crystal structure was not previously available in the Cambridge Structural Database.
Digital Object Identifier (DOI)
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