Gene Transfer Between Lactobacillus Species
Author Information
Author(s): Nicolas Pierre, Bessières Philippe, Ehrlich S Dusko, Maguin Emmanuelle, van de Guchte Maarten
Primary Institution: INRA, Mathématique Informatique et Génome, UR1077, Jouy en Josas, France
Hypothesis
How does horizontal gene transfer affect the phylogenetic relationships between Lactobacillus species?
Conclusion
The study reveals extensive horizontal gene transfer between Lactobacillus acidophilus and Lactobacillus johnsonii, suggesting significant evolutionary implications.
Supporting Evidence
- High confidence phylogenetic trees support the 16S-rRNA tree in a 3:2 ratio.
- Gene transfer may have affected as much as 40% of the core genome genes.
- Phylogenetic incongruence suggests extensive horizontal gene transfer.
Takeaway
This study shows that two types of bacteria can share genes with each other, which can change how we think about their family tree.
Methodology
The study analyzed 401 protein phylogenetic trees to assess gene transfer between Lactobacillus species.
Potential Biases
Potential biases in gene function classification could affect the interpretation of gene transfer events.
Limitations
The study may not account for all potential sources of phylogenetic incongruence.
Participant Demographics
The study focuses on Lactobacillus species found in the gastrointestinal tract and yogurt.
Statistical Information
P-Value
p ~ 0.006
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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