Evaluation of 17-mm St. Jude Medical Regent prosthetic aortic heart valves by rest and dobutamine stress echocardiography
2006

Evaluation of 17-mm St. Jude Medical Regent prosthetic aortic heart valves

Sample size: 19 publication Evidence: moderate

Author Information

Author(s): Minardi Giovanni, Manzara Carla, Creazzo Vittorio, Maselli Daniele, Casali Giovanni, Pulignano Giovanni, Musumeci Francesco

Primary Institution: Department of Cardiology and Cardiovascular Surgery, Azienda Ospedaliera, S.Camillo-Forlanini, Rome, Italy

Hypothesis

This study was carried out to evaluate rest and Dobutamine stress echocardiography (DSE) hemodynamic response of 17-mm St. Jude Medical Regent (SJMR-17 mm) in relatively aged patients.

Conclusion

SJMR 17-mm prostheses can be safely implanted in aortic position in relatively aged patients, offering satisfactory hemodynamic performance at rest and under DSE.

Supporting Evidence

  • At rest, the mean pressure gradients were 29.2 ± 7.1 mmHg and 16.6 ± 5.8 mmHg.
  • Left ventricular mass decreased significantly from pre-operative values of 258 ± 43g to 191 ± 23.8g.
  • Dobutamine stress echocardiography increased heart rate, cardiac output, and ejection fraction significantly.

Takeaway

Doctors studied how a special heart valve works in older patients to see if it works well when they are resting and when they are under stress. They found it works just fine!

Methodology

The study involved 19 patients who underwent echocardiography at rest and during dobutamine stress to evaluate various hemodynamic parameters.

Limitations

The small number of patients examined demonstrates the rarity of patients potentially requiring a 17 mm aortic valve prosthesis.

Participant Demographics

The study population consisted of 19 patients (2 men, 17 women) with a mean age of 69.2 ± 7.3 years.

Statistical Information

P-Value

p<0.001

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1749-8090-1-27

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