Myocardial ASL Perfusion Reserve Test Identifies Ischemic Heart Segments
Author Information
Author(s): Zun Zungho, Jao Terrence, Smith Ning, Varadarajan Padmini, Pai Ramdas G, Wong Eric C, Nayak Krishna S
Primary Institution: University of Southern California
Hypothesis
Can myocardial arterial spin labeling (ASL) identify ischemic myocardial segments due to stenosis in coronary arteries as detected by X-ray angiography?
Conclusion
Myocardial ASL can identify ischemic myocardial segments similarly to X-ray angiography, with no significant differences found.
Supporting Evidence
- Ten of the twenty-nine patients had significant stenosis on X-ray angiography.
- There was visual agreement in identifying ischemic segments between ASL and X-ray angiography.
- The average standard deviation of physiological noise was 0.22 ml/g/min at rest and 0.42 ml/g/min during stress.
Takeaway
This study shows that a special imaging technique can help doctors see which parts of the heart are not getting enough blood.
Methodology
Twenty-nine patients underwent myocardial ASL measurements at rest and during adenosine stress using a GE Signa 3T scanner.
Limitations
The study had a small sample size and only included patients scheduled for routine cardiac MR and X-ray angiography.
Statistical Information
P-Value
1.0000
Statistical Significance
p = 1.0000
Digital Object Identifier (DOI)
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