Impact of Acute Kidney Injury on Survival in Patients Undergoing Lung Assist Treatment
Author Information
Author(s): Kielstein Jan T, Tolk Soeren, Hafer Carsten, Heiden Anna, Wiesner Olaf, Kühn Christian, Hadem Johannes, Hoeper Marius M, Fischer Stefan
Primary Institution: Medical School Hannover, Germany
Hypothesis
How does acute kidney injury requiring extended dialysis affect the survival of patients undergoing interventional lung assist treatment?
Conclusion
Acute kidney injury requiring extended dialysis significantly increases mortality in ICU patients undergoing interventional lung assist treatment.
Supporting Evidence
- 28 day survival of patients requiring extended dialysis was only 19%.
- Patients without extended dialysis had a 28 day survival of 40%.
- One year survival for patients on extended dialysis was 5%, compared to 25% for those not requiring dialysis.
Takeaway
If someone has kidney problems and needs special treatment while getting help to breathe, they are more likely to not survive compared to those who don't need that extra help.
Methodology
Retrospective analysis of patients undergoing interventional lung assist treatment at a tertiary care hospital from 2005 to 2009.
Potential Biases
The inclusion of a heterogeneous patient population may introduce variability in outcomes.
Limitations
The study is retrospective and conducted at a single center, with a limited number of patients.
Participant Demographics
61 patients (31 female, 30 male), median age 40 years.
Statistical Information
P-Value
p = 0.001 for 28 day survival comparison
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website