Placental Site Trophoblastic Tumour: A Rare but Curable Cancer
Author Information
Author(s): Gillespie A M, Liyim D, Goepel J R, Coleman R E, Hancock B W
Primary Institution: Yorkshire Cancer Research Department of Clinical Oncology, Weston Park Hospital, Sheffield, UK
Hypothesis
Placental site trophoblastic tumour (PSTT) is a rare form of gestational trophoblastic disease that can be effectively treated.
Conclusion
Most patients with early-stage PSTT can be successfully treated, but those with advanced disease have a poor prognosis.
Supporting Evidence
- Seven cases of PSTT were managed at the Trophoblastic Disease Screening and Treatment Centre.
- Three patients had disease confined to the uterus and were treated successfully with hysterectomy.
- Two patients with pulmonary metastases were treated with chemotherapy and are alive and well.
- Two patients with advanced disease died despite treatment.
Takeaway
This study looked at a rare cancer called placental site trophoblastic tumour, and found that some patients can be cured with surgery, while others with more advanced disease may not survive.
Methodology
Analysis of all cases of PSTT managed at the Trophoblastic Disease Screening and Treatment Centre from 1984 to 1996.
Limitations
The study is limited by the small sample size of only seven cases.
Participant Demographics
Patients managed at a specialized treatment center for gestational trophoblastic disease.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website