Leptin and adiponectin in relation to body fat percentage, waist to hip ratio and the apoB/apoA1 ratio in Asian Indian and Caucasian men and women
2006

Leptin and Adiponectin Levels in Asian Indian and Caucasian Adults

Sample size: 54 publication 10 minutes Evidence: moderate

Author Information

Author(s): Jessica Smith, Maha Al-Amri, Allan Sniderman, Katherine Cianflone

Primary Institution: McGill University Health Centre

Hypothesis

How do leptin and adiponectin relate to cardiovascular disease risk factors in Asian Indian men and women compared to Caucasian men and women?

Conclusion

Asian Indian men and women have higher leptin and lower adiponectin levels than their Caucasian counterparts, indicating a strong relationship with increased cardiovascular disease risk.

Supporting Evidence

  • Asian Indian men had higher leptin levels than Caucasian men.
  • Asian Indian women had lower adiponectin levels than Caucasian women.
  • Leptin levels correlated positively with body fat percentage and waist circumference.
  • Adiponectin levels correlated negatively with waist to hip ratio.

Takeaway

This study found that Indian men and women have more leptin and less adiponectin than Caucasian men and women, which may increase their risk of heart disease.

Methodology

A cross-sectional study measuring leptin, adiponectin, lipoproteins, and anthropometric parameters in Asian Indian and Caucasian adults.

Potential Biases

Potential selection bias due to recruitment methods and exclusion criteria.

Limitations

The study is limited to a specific age range and geographic location, which may not be generalizable to all populations.

Participant Demographics

Participants were Asian Indian and Caucasian men and women aged 20 to 60 living in Montreal, Canada.

Statistical Information

P-Value

p<0.0001

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1743-7075-3-18

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