Sulfamethoxazole/Trimethoprim induced liver failure: a case report
2008
Case of Liver Failure from Antibiotic
Sample size: 1
publication
Evidence: low
Author Information
Author(s): Abusin Salaheldin, Johnson Swapna
Primary Institution: Stroger Hospital of Cook County
Hypothesis
Can sulfamethoxazole/trimethoprim cause acute liver failure?
Conclusion
The case illustrates that sulfamethoxazole/trimethoprim can lead to acute liver failure, but recovery is possible with supportive care.
Supporting Evidence
- The patient developed jaundice and acute liver failure after taking the antibiotic.
- Her liver function improved with supportive care.
- The diagnosis was made based on the timing of symptoms and exclusion of other causes.
Takeaway
A young woman got very sick after taking a common antibiotic, but she got better with help from doctors.
Methodology
Case report detailing clinical presentation, laboratory findings, and recovery of a patient.
Limitations
Only one case is reported, limiting generalizability.
Participant Demographics
22-year-old female, previously healthy.
Digital Object Identifier (DOI)
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