Research Progress of Regulatory Cell Death in Coronary Microembolization
Author Information
Author(s): Chang Chen, Huang Wan-Zhong, Cai Ru-Ping, Mo Li-Rong, Wu Qiang, Su Qiang
Hypothesis
The review aims to summarize the molecular mechanisms underlying coronary microembolization (CME) and the role of regulatory cell death (RCD) in this process.
Conclusion
Understanding the mechanisms of regulatory cell death may lead to new prevention and treatment strategies for coronary microembolization.
Supporting Evidence
- Coronary microembolization is a major complication during percutaneous coronary intervention, with an incidence of up to 25%.
- Regulatory cell death plays a significant role in mediating inflammatory responses and cell death in coronary microembolization.
- Different forms of regulatory cell death are associated with distinct signaling pathways that may be targeted for therapeutic interventions.
Takeaway
This study looks at how certain types of cell death affect heart problems caused by tiny blood clots in the heart's small blood vessels.
Methodology
This is a review article summarizing existing research on regulatory cell death and its implications in coronary microembolization.
Limitations
The review primarily focuses on apoptosis, autophagy, pyroptosis, and ferroptosis, neglecting other forms of regulatory cell death.
Digital Object Identifier (DOI)
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