Prevalence and Factors Associated with Leishmania infantum Infection of Dogs from an Urban Area of Brazil as Identified by Molecular Methods
2011

Prevalence and Factors Associated with Leishmania infantum Infection in Dogs in Brazil

Sample size: 1443 publication 10 minutes Evidence: moderate

Author Information

Author(s): Coura-Vital Wendel, Marques Marcos José, Veloso Vanja Maria, Roatt Bruno Mendes, Aguiar-Soares Rodrigo Dian de Oliveira, Reis Levi Eduardo Soares, Braga Samuel Leôncio, Morais Maria Helena Franco, Reis Alexandre Barbosa, Carneiro Mariângela

Primary Institution: Universidade Federal de Minas Gerais

Hypothesis

What are the prevalence and associated factors of Leishmania infantum infection in dogs in an urban area of Brazil?

Conclusion

The study found a high prevalence of L. infantum infection in dogs, with socioeconomic factors and owner knowledge influencing infection rates.

Supporting Evidence

  • 230 dogs were seropositive in at least one ELISA test.
  • 356 dogs were positive for L. infantum DNA by PCR-RFLP.
  • Factors associated with infection included low family income and owner knowledge of the vector.

Takeaway

This study shows that many dogs in Brazil are infected with a parasite that can cause disease in humans, and certain factors like family income and owner knowledge can affect this.

Methodology

A cross-sectional study was conducted where blood samples were collected from 1,443 dogs, and serological and molecular methods were used to determine infection status.

Potential Biases

Potential bias due to non-probabilistic sampling and reliance on owner-reported data.

Limitations

The study's cross-sectional design limits causal inferences, and the sampling was not probabilistic.

Participant Demographics

The study included 1,443 dogs from urban households in Belo Horizonte, Brazil.

Statistical Information

P-Value

p<0.05

Confidence Interval

95% CI 1.4–3.8

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pntd.0001291

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