The repertoire of ICE in prokaryotes underscores the unity, diversity and ubiquity of conjugation
2011

A Global Overview of Bacterial Sexuality

Sample size: 3500 publication Evidence: moderate

Author Information

Author(s): Mark Achtman

Primary Institution: Environmental Research Institute, University College Cork, Cork, Ireland

Hypothesis

What are the genetic elements responsible for conjugation in bacteria?

Conclusion

Conjugation is a common mechanism for gene transfer among bacteria and possibly archaea.

Supporting Evidence

  • ICEs were found to be twice as frequent as conjugative plasmids.
  • ICEs were present in over 50% of genomes from bacteroidetes.
  • Conjugation can blur phylogenetic patterns among bacteria.

Takeaway

Bacteria can share genes with each other through a process called conjugation, which is like passing notes in class. This helps them adapt and survive better.

Methodology

The study scanned the genomes of 1,207 chromosomes and 2,282 plasmids to identify conjugation proteins.

Limitations

The study may not have identified all types of conjugation proteins due to limitations in the bioinformatic pipeline.

Digital Object Identifier (DOI)

10.1371/journal.pgen.1002222

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