Impact of Age on Troponin Levels Without Obstructive Coronary Lesions
Author Information
Author(s): Abumayyaleh Mohammad, Schlettert Clara, Materzok Daniel, Mügge Andreas, Hamdani Nazha, Akin Ibrahim, Aweimer Assem, El-Battrawy Ibrahim, Isoda Kikuo
Primary Institution: University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University
Hypothesis
How does age affect the outcomes of patients with elevated troponin levels without obstructive coronary lesions?
Conclusion
Older patients with elevated troponin levels without obstructive lesions experience more adverse cardiovascular events and higher mortality rates compared to younger patients.
Supporting Evidence
- Older patients had a higher rate of major adverse cardiovascular events during hospitalization.
- Cardiovascular mortality was higher in older patients at long-term follow-up.
- The study included 373 patients screened from 24,775 for elevated troponin levels.
- Patients were categorized into four age groups for analysis.
- Non-sustained ventricular tachycardia was more common in the 51-60 age group.
Takeaway
As people get older, they are more likely to have heart problems even if their arteries aren't blocked, and they may not do as well as younger people.
Methodology
This study analyzed data from 373 patients with elevated troponin levels without obstructive lesions, categorized by age, and assessed their in-hospital complications and long-term outcomes.
Potential Biases
Potential selection bias due to the retrospective nature and single-center design.
Limitations
The study is monocentric and retrospective, and not all patients underwent advanced imaging techniques.
Participant Demographics
Mean age of 63 years, 49.6% male, with patients categorized into four age groups.
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website