Tumor microenvironment in oral squamous cell carcinoma
2024

Tumor Microenvironment in Oral Squamous Cell Carcinoma

publication Evidence: moderate

Author Information

Author(s): Li Chenxi, Dong Xiaodan, Li Bo

Primary Institution: Jilin University, Changchun, China

Hypothesis

The interactions among cells in the tumor microenvironment (TME) significantly influence the progression of oral squamous cell carcinoma (OSCC).

Conclusion

The study highlights the complex roles of various cellular components in the TME and their implications for OSCC treatment strategies.

Supporting Evidence

  • OSCC is associated with a poor prognosis and high mortality due to limitations of existing therapies.
  • The TME plays a significant role in OSCC progression through complex cellular interactions.
  • Understanding TME interactions can lead to new treatment strategies for OSCC.

Takeaway

This study explains how different cells in the tumor environment work together to help oral cancer grow and spread, suggesting new ways to treat it.

Methodology

This is a review summarizing current literature on the role of cellular components in the TME of OSCC.

Potential Biases

Potential bias in the selection of studies reviewed may affect the conclusions drawn.

Limitations

The review does not provide new experimental data and relies on existing literature, which may have varying quality.

Digital Object Identifier (DOI)

10.3389/fimmu.2024.1485174

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