Natural relapses in vivax malaria induced by Anopheles mosquitoes
2008

Malaria Relapses Induced by Mosquitoes in Finland

publication Evidence: moderate

Author Information

Author(s): Huldén Lena, Huldén Larry, Heliövaara Kari

Primary Institution: University of Helsinki

Hypothesis

The study aims to explain the underlying cause of relapses and to determine the length of the incubation time of P. vivax malaria in Finland.

Conclusion

The study concludes that uninfected Anopheles mosquitoes induce relapses of vivax malaria in humans, with a significant correlation between malaria deaths and June-July temperatures.

Supporting Evidence

  • Malaria cases show an increasing correlation with June-July temperatures.
  • The longest incubation time identified was 8 years and 7 months.
  • Uninfected Anopheles mosquitoes are involved in malaria deaths in August and September.

Takeaway

Mosquitoes can wake up sleeping malaria parasites in people, causing them to get sick again even if they seemed fine for a long time.

Methodology

The study analyzed historical data of malaria deaths from 1750 to 1850 and correlated it with June and July temperatures.

Limitations

The study relies on historical data, which may not account for all variables affecting malaria transmission.

Participant Demographics

The study focuses on malaria cases in Finland during the 18th and 19th centuries.

Digital Object Identifier (DOI)

10.1186/1475-2875-7-64

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