Improved cardiac arterial spin labelling in the mouse heart by optimisation of acquisition and analysis
2011
Improved Cardiac Imaging in Mice
publication
Author Information
Author(s): Campbell Adrienne E, Price Anthony N, Wells Jack A, Lythgoe Mark F, Ordidge Roger J
Primary Institution: University College London
Hypothesis
Can a time-efficient segmented k-space arterial spin labelling sequence improve data quality in mouse heart imaging?
Conclusion
The study successfully implemented a time-efficient method for cardiac ASL data acquisition in mice, enhancing data quality by using a data logger.
Supporting Evidence
- The average number of missed ECG peaks was reduced from 2 to 0 with the data logger.
- The method improved the quality of anatomical images and T1 maps.
Takeaway
This study found a better way to take pictures of mouse hearts that helps doctors see how well the heart is working without hurting the mouse.
Methodology
A segmented k-space ASL sequence was used with a data logger to improve ECG gating and reduce respiration-related image corruption.
Digital Object Identifier (DOI)
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