Simultaneous Combined Pancreas and Kidney Allotransplantation in the Pig

Simultaneous Combined Pancreas and Kidney Allotransplantation in Pigs

Sample size: 32 publication Evidence: moderate

Author Information

Author(s): P.G. Sfikakis, P.J. Tzardis, R.W.G. Gruessner, D.E.R. Sutherland

Primary Institution: Dept. of Surgery, University of Minnesota

Hypothesis

The new technique for en bloc simultaneous pancreas and kidney transplantation will decrease preservation time, operation time, and clamp time.

Conclusion

The proposed technique could be used in humans, particularly for adult uremic diabetic patients receiving a combined pancreas/kidney allotransplant from a pediatric cadaver donor.

Supporting Evidence

  • The technique saves about 50 minutes of operating and clamp time.
  • None of the recipients died from technical complications.

Takeaway

Scientists found a way to transplant a pancreas and kidney together in pigs that takes less time and is safer.

Methodology

The donor aorta and other vessels were anastomosed en bloc to the recipient's aorta, and the donor duodenum was anastomosed to the bladder for monitoring.

Participant Demographics

Yorkshire pigs

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