SpliceMiner: A Tool for Analyzing Splice Variants
Author Information
Author(s): Ari B. Kahn, Michael C. Ryan, Hongfang Liu, Barry R. Zeeberg, D. Curtis Jamison, John N. Weinstein
Primary Institution: George Mason University
Hypothesis
How can we improve the analysis of microarray expression data by incorporating splice variant information?
Conclusion
SpliceMiner enhances microarray analysis by providing access to a comprehensive database of splice variants, allowing for better interpretation of gene expression data.
Supporting Evidence
- SpliceMiner allows for both interactive and batch queries of splice variant data.
- The tool integrates splice variant information into microarray analysis pipelines.
- SpliceMiner provides a user-friendly interface for exploring splice variant information.
Takeaway
SpliceMiner is a tool that helps scientists understand different versions of genes that can be made from the same DNA, which is important for studying how genes work.
Methodology
SpliceMiner was developed as a web interface for querying the Evidence Viewer Database (EVDB), which contains splice variant data for human genes.
Limitations
The database may not include all splice variants, particularly for genes that are not well-studied or validated.
Digital Object Identifier (DOI)
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