Carotid Artery Thickness in Infants of Diabetic Mothers
Author Information
Author(s): Atabek Mehmet Emre, Hasret Çağan Havva, Selver Eklioğlu Beray, Oran Bülent
Primary Institution: Selçuk University School of Medicine
Hypothesis
Are infants of diabetic mothers at increased risk for atherosclerosis as indicated by carotid artery intima-media thickness?
Conclusion
This study found no significant differences in carotid artery intima-media thickness between infants of diabetic mothers and healthy controls.
Supporting Evidence
- LVMI was higher in LGA IDM compared to AGA IDM and controls.
- CA-IMT was not significantly different between the groups.
- Serum lipid and insulin levels were higher in LGA IDM compared to AGA IDM and controls.
- No correlations were found between CA-IMT, LVMI, and atherosclerotic risk factors.
Takeaway
The study looked at babies born to diabetic mothers and found that their blood vessels didn't show signs of thickening, which is usually a sign of heart problems.
Methodology
The study included 30 infants of diabetic mothers and 25 healthy controls, measuring carotid artery intima-media thickness and left ventricular mass index using echocardiography.
Potential Biases
The study was conducted by a single clinician who was unaware of the subjects' laboratory values, which may reduce bias.
Limitations
The small sample size and potential methodological issues in measuring carotid artery thickness in neonates.
Participant Demographics
30 infants of diabetic mothers (14 AGA, 16 LGA) and 25 healthy controls.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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