Noninvasive Brain Stimulation for Improving Cognitive Deficits and Clinical Symptoms in Attention-Deficit/Hyperactivity Disorder: A Systematic Review and Meta-Analysis
2024

Noninvasive Brain Stimulation for ADHD: A Review

Sample size: 582 publication 10 minutes Evidence: moderate

Author Information

Author(s): Yin Yao, Wang Xueke, Feng Tingyong

Primary Institution: Southwest University, Chongqing, China

Hypothesis

This meta-analysis seeks to assess the efficacy of noninvasive brain stimulation (NIBS) in improving cognitive deficits and clinical symptoms in individuals with ADHD.

Conclusion

The findings highlight NIBS as a promising adjunctive therapy for managing ADHD, showing significant improvements in inhibitory control, working memory, and inattention with tDCS.

Supporting Evidence

  • tDCS showed significant improvements in inhibitory control, working memory, and inattention.
  • rTMS did not demonstrate significant therapeutic benefits for ADHD symptoms.
  • Subgroup analyses indicated that tDCS was particularly effective in children and those who were medicated.

Takeaway

This study found that certain brain stimulation techniques can help kids with ADHD focus better and remember things more easily.

Methodology

The study systematically searched five databases for randomized controlled trials and conducted a meta-analytical synthesis using RevMan 5.4.1.

Potential Biases

Most studies showed a low risk of bias, but some had concerns regarding performance bias.

Limitations

The study did not conduct a meta-analysis on tACS and tRNS due to a limited number of studies and various outcomes.

Participant Demographics

The analysis included children and adults diagnosed with ADHD, with a mean age of approximately 31.6 years.

Statistical Information

P-Value

0.02

Confidence Interval

[−0.39, −0.04]

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.3390/brainsci14121237

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