Huangqi Injection for Chronic Heart Failure
Author Information
Author(s): Fu Shufei, Zhang Junhua, Menniti-Ippolito Francesca, Gao Xiumei, Galeotti Francesca, Massari Marco, Hu Limin, Zhang Boli, Ferrelli Rita, Fauci Alice, Firenzuoli Fabio, Shang Hongcai, Guerra Ranieri, Raschetti Roberto
Primary Institution: Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China
Hypothesis
To evaluate the efficacy and safety of Huangqi injection for CHF according to the available scientific knowledge.
Conclusion
The available studies are not adequate to draw a conclusion on the efficacy and safety of Huangqi injection.
Supporting Evidence
- The review included 62 RCTs and quasi-RCTs conducted in China.
- Only one study evaluated the outcomes for drug efficacy after an adequate period of time.
- The overall level of TCM clinical research needs to be improved.
Takeaway
This study looked at a traditional Chinese medicine called Huangqi injection to see if it helps people with heart failure, but the results were not clear.
Methodology
A systematic review of randomized and quasi-randomized clinical trials regarding Huangqi injection for CHF was conducted.
Potential Biases
There was a risk of selection bias due to inadequate randomization and allocation concealment.
Limitations
The methodological quality of the trials was low, and many did not specify inclusion and exclusion criteria.
Participant Demographics
The mean age of participants was 60.9 years, with 63.3% being male.
Statistical Information
Statistical Significance
p<0.01
Digital Object Identifier (DOI)
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