Organic Papers 10α-Hydroxy-4,9-dimethyl-13-[(pyrrolidin-1-yl)methyl]-3,8,15-trioxatetracyclo[10.3.0.02,4.07,9]pentadecan-14-one C19H29NO5
2011
Synthesis and Structure of a New Compound from Anvillea radiata
publication
Evidence: moderate
Author Information
Author(s): Moumou Mohamed, Benharref Ahmed, Berraho Moha, Avignant Daniel, Oudahmane Abdelghani, Akssira Mohamed
Primary Institution: Laboratoire de Chimie Biomoléculaire, Substances Naturelles et Réactivité, URAC 16, Faculté des Sciences Semlalia, Marrakech, Morocco
Conclusion
The study successfully synthesized a new compound from 9α-hydroxypartenolide with a high yield and characterized its molecular structure.
Supporting Evidence
- The compound was synthesized with a yield of 95%.
- An intramolecular O—H⋯N hydrogen bond stabilizes the molecular conformation.
- The molecular structure shows two fused rings with different conformations.
Takeaway
Scientists made a new chemical from a plant and figured out what it looks like. It's like building with blocks to create something new!
Methodology
The compound was synthesized through a series of chemical reactions involving 9α-hydroxypartenolide and pyrrolidine, followed by crystallization.
Digital Object Identifier (DOI)
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