A phylogenomic profile of globins
2006

A phylogenomic profile of globins

Sample size: 320 publication Evidence: high

Author Information

Author(s): Vinogradov Serge N, Hoogewijs David, Bailly Xavier, Arredondo-Peter Raúl, Gough Julian, Dewilde Sylvia, Moens Luc, Vanfleteren Jacques R

Hypothesis

The study investigates the distribution and evolution of globins across different kingdoms of life.

Conclusion

Globins are mostly enzymes and less frequently sensors, and the transport of oxygen likely developed with the emergence of multicellular organisms.

Supporting Evidence

  • Globins occur in all three kingdoms of life.
  • Only ~25% of archaea have globins.
  • Over 90% of eukaryotes have globins.
  • Globins appear to be mostly absent in certain bacterial groups.

Takeaway

This study looked at different types of globins in various living things and found that most have globins, which help with functions like transporting oxygen.

Methodology

The study involved a census of globins in 26 archaeal, 245 bacterial, and 49 eukaryote genomes.

Limitations

The absence of globins is certain only when a complete genome is searched and no sequence is found.

Digital Object Identifier (DOI)

10.1186/1471-2148-6-31

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