Health-related quality of life and distress in cancer patients: results from a large randomised study
2008

Health-related quality of life and distress in cancer patients

Sample size: 481 publication Evidence: moderate

Author Information

Author(s): Johansson B, Brandberg Y, Hellbom M, Persson C, Petersson L-M, Berglund G, Glimelius B

Primary Institution: Uppsala University

Hypothesis

To compare the effectiveness of individual support, group rehabilitation and a combination of the two in improving health-related quality of life (HRQOL) and psychological well-being in cancer patients during 24 months after diagnosis, as compared with standard care.

Conclusion

The interventions did not improve HRQOL or psychological well-being in newly diagnosed cancer patients compared to standard care.

Supporting Evidence

  • At 3 months, the study sample reported an HRQOL comparable with the normal population.
  • Many cancer patients are able to manage their cancer-related concerns with the support available from standard care.
  • The interventions evaluated did not show significant improvements in HRQOL or psychological well-being.

Takeaway

This study looked at how different types of support help cancer patients feel better. It found that many patients do just fine with the usual care they get.

Methodology

Patients were randomly assigned to one of four groups: individual support, group rehabilitation, a combination of both, or standard care, with assessments at multiple time points over 24 months.

Potential Biases

Older patients were less likely to participate, which may skew results.

Limitations

The study may lack data from vulnerable patients and could be affected by a Hawthorne effect.

Participant Demographics

The study included newly diagnosed cancer patients, primarily with breast, gastrointestinal, or prostate cancer.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1038/sj.bjc.6604789

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