Honey's Effect on Healing Nonhealing Wounds
Author Information
Author(s): Ananya Barui, Provas Banerjee, Raunak Kumar Das, Shyamal Kumar Basu, Santanu Dhara, Jyotirmoy Chatterjee
Primary Institution: Indian Institute of Technology, Kharagpur
Hypothesis
The study evaluates the impact of honey-based occlusive dressing on nonhealing traumatic lower limb wounds.
Conclusion
Honey dressing significantly improved the healing of nonhealing lower limb wounds by enhancing protein expressions related to tissue repair.
Supporting Evidence
- Honey dressing led to a significant decrease in pain and malodor within 11-15 days.
- Histopathological evaluations showed improved epithelial and connective tissue features post-treatment.
- The expression of p63+ cells increased towards normal levels after honey application.
Takeaway
Using honey on wounds helps them heal better and faster, making them less painful and smelly.
Methodology
The study involved applying honey-based dressings to 34 patients with nonhealing lower limb wounds and evaluating clinical and histopathological changes over time.
Participant Demographics
Patients aged 16–65 years with nonhealing lower extremity wounds.
Statistical Information
P-Value
<0.0001
Statistical Significance
p<0.0001
Digital Object Identifier (DOI)
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