The VEPRO trial: A cross-over randomised controlled trial comparing 2 progressive lenses for patients with presbyopia
2008

Comparing Two Types of Progressive Lenses for Presbyopia

Sample size: 127 publication Evidence: moderate

Author Information

Author(s): Boutron Isabelle, Touizer Caroline, Pitrou Isabelle, Roy Carine, Ravaud Philippe

Primary Institution: INSERM, U738, Paris, France

Hypothesis

Is there a difference in patient preference and visual performance between new-generation and older-generation progressive lenses for presbyopia?

Conclusion

Patients with presbyopia had slightly higher preference for the new-generation than older-generation lens, with no difference in lens groups for most of the visual outcomes assessed.

Supporting Evidence

  • 57.9% of patients preferred the new-generation lenses.
  • The study included 127 patients randomized to wear two types of lenses.
  • The primary outcome was patient preference assessed at week 8.

Takeaway

This study looked at two types of glasses for people who have trouble seeing up close. Most people liked the newer glasses better, but both types worked similarly for most vision tasks.

Methodology

A multicenter cross-over randomized controlled trial comparing two types of progressive lenses over two 4-week periods.

Potential Biases

Potential bias due to the subjective nature of patient-reported outcomes.

Limitations

The study faced challenges in ensuring adequate blinding due to the engraved marks on the lenses.

Participant Demographics

Participants were aged 43-60 years, already wearing progressive lenses, and able to understand French.

Statistical Information

P-Value

0.01

Statistical Significance

p = 0.01

Digital Object Identifier (DOI)

10.1186/1745-6215-9-54

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