Surgical Outcomes for Colon and Rectal Cancer Over a Decade
Author Information
Author(s): Andreoni Bruno, Chiappa Antonio, Bertani Emilio, Bellomi Massimo, Orecchia Roberto, Zampino MariaGiulia, Fazio Nicola, Venturino Marco, Orsi Franco, Sonzogni Angelica, Pace Ugo, Monfardini Lorenzo
Primary Institution: European Institute of Oncology, University of Milano, Italy
Hypothesis
What are the surgical morbidity and long-term outcomes of colorectal cancer surgery in an unselected group of patients?
Conclusion
The study shows that a uniform follow-up policy in colorectal cancer surgery leads to low mortality rates and high survival rates.
Supporting Evidence
- Postoperative complications occurred in 38% of the total group.
- The 5-year overall survival rates were 71% for all cases.
- Mortality rate was 0.8%, with 1.3% for colon cancer and 0% for rectal cancer.
- R0 resections were achieved in 77.4% of patients.
- 5-year disease-free survival rate was 73% for R0 patients.
Takeaway
Doctors looked at how well surgery works for people with colon and rectal cancer over ten years, and they found that most patients do well after surgery.
Methodology
The study evaluated 902 patients with primary colorectal cancer, analyzing perioperative mortality, morbidity, overall survival, and recurrence rates.
Potential Biases
Potential bias due to the study being conducted at a single center with a specific patient population.
Limitations
The study is limited to a single institution and may not be generalizable to other settings.
Participant Demographics
489 men and 413 women, mean age 63 years (range 24–88 years).
Statistical Information
P-Value
p<0.0001
Confidence Interval
95% CI not specified
Statistical Significance
p<0.0001
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website